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G-quartets assembly within a G-rich DNA flap. A possible event at the center of the HIV-1 genome

Stretches of guanines can associate in vitro through Hoogsteen hydrogen bonding to form four-stranded structures. In the HIV-1 central DNA flap, generated by reverse transcriptase at the end of retrotranscription, both the two 99 nt-long overlapping (+) strands contain two adjacent tracts of guanine...

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Detalhes bibliográficos
Main Authors: Lyonnais, Sébastien, Hounsou, Candide, Teulade-Fichou, Marie-Paule, Jeusset, Josette, Cam, Eric Le, Mirambeau, Gilles
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC137959/
https://ncbi.nlm.nih.gov/pubmed/12466553
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