Mouse-Human Heterokaryons Support Efficient Human Immunodeficiency Virus Type 1 Assembly

Murine cells do not support human immunodeficiency virus type 1 (HIV-1) replication because of blocks to virus entry, proviral expression, and virion assembly. In murine 3T3 fibroblasts, the block to HIV-1 entry is relieved by the introduction of human CD4 and CCR5 or CXCR4, and proviral expression...

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Detalhes bibliográficos
Main Authors: Mariani, Roberto, Rasala, Beth A., Rutter, Gabriel, Wiegers, Klaus, Brandt, Stephanie M., Kräusslich, Hans-Georg, Landau, Nathaniel R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114108/
https://ncbi.nlm.nih.gov/pubmed/11238841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.7.3141-3151.2001
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