Highly Reliable Heterologous System for Evaluating Resistance of Clinical Herpes Simplex Virus Isolates to Nucleoside Analogues

Clinical resistance of herpes simplex virus (HSV) types 1 and 2 to acyclovir (ACV) is usually caused by the presence of point mutations within the coding region of the viral thymidine kinase (TK) gene. The distinction between viral TK mutations involved in ACV resistance or part of viral polymorphis...

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Vydáno v:	J Virol
Hlavní autoři:	Bestman-Smith, Julie, Schmit, Isabelle, Papadopoulou, Barbara, Boivin, Guy
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2001
Témata:	Vaccines and Antiviral Agents
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114104/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11238837/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.7.3105-3110.2001
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