Highly Reliable Heterologous System for Evaluating Resistance of Clinical Herpes Simplex Virus Isolates to Nucleoside Analogues

Clinical resistance of herpes simplex virus (HSV) types 1 and 2 to acyclovir (ACV) is usually caused by the presence of point mutations within the coding region of the viral thymidine kinase (TK) gene. The distinction between viral TK mutations involved in ACV resistance or part of viral polymorphis...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Bestman-Smith, Julie, Schmit, Isabelle, Papadopoulou, Barbara, Boivin, Guy
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Vaccines and Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114104/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11238837/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.7.3105-3110.2001
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