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Tiam1-IRSp53 Complex Formation Directs Specificity of Rac-Mediated Actin Cytoskeleton Regulation

The exchange factor Tiam1 regulates multiple cellular functions by activating the Rac GTPase. Active Rac has various effects in cells, including alteration of actin cytoskeleton and gene expression, via binding to and modulating the activity of diverse effector proteins. How individual Rac effectors...

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Detalles Bibliográficos
Main Authors: Connolly, Beth A., Rice, Jared, Feig, Larry A., Buchsbaum, Rachel J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140638/
https://ncbi.nlm.nih.gov/pubmed/15899863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.11.4602-4614.2005
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