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Raf-1 Serine 338 Phosphorylation Plays a Key Role in Adhesion-Dependent Activation of Extracellular Signal-Regulated Kinase by Epidermal Growth Factor
Activation of the extracellular signal-regulated kinase (ERK) 1/2 cascade by polypeptide growth factors is tightly coupled to adhesion to extracellular matrix in nontransformed cells. Raf-1, the initial kinase in this cascade, is intricately regulated by phosphorylation, localization, and molecular...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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American Society for Microbiology
2005
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1140616/ https://ncbi.nlm.nih.gov/pubmed/15899852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.11.4466-4475.2005 |
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