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Effects of a High-Fat Meal on the Relative Oral Bioavailability of Piperaquine
Piperaquine (PQ) is an antimalarial drug whose high lipid solubility suggests that its absorption can be increased by a high-fat meal. We examined the pharmacokinetics of PQ phosphate (500 mg given orally) in the fasting state and after a high-fat meal in eight healthy Caucasian volunteers (randomiz...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2005
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1140540/ https://ncbi.nlm.nih.gov/pubmed/15917540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.6.2407-2411.2005 |
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