Bactericidal Activity of the Nitroimidazopyran PA-824 in a Murine Model of Tuberculosis

The nitroimidazopyran PA-824 has potent in vitro activity against Mycobacterium tuberculosis, a narrow spectrum of activity limited primarily to the M. tuberculosis complex, and no demonstrable cross-resistance to a variety of antituberculosis drugs. In a series of experiments, we sequentially chara...

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Main Authors: Tyagi, Sandeep, Nuermberger, E., Yoshimatsu, T., Williams, K., Rosenthal, I., Lounis, N., Bishai, W., Grosset, J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2005
Teme:
Experimental Therapeutics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140529/
https://ncbi.nlm.nih.gov/pubmed/15917523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.6.2289-2293.2005
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