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Cross-reactivity and conformational multiplicity of an anti-polycyclic aromatic hydrocarbon mAb

Cross-reactivity and multispecific functionality of antibodies play a central role in the immune system. The Ab's promiscuity is attributed to structural flexibility and conformational multiplicity of its binding sites governed by the rearrangement of hydrogen bonding centers. However, antibodi...

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Detalhes bibliográficos
Main Authors: Grubor, Nenad M., Hayes, John, Small, Gerald J., Jankowiak, Ryszard
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140447/
https://ncbi.nlm.nih.gov/pubmed/15888556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502540102
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