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Cross-reactivity and conformational multiplicity of an anti-polycyclic aromatic hydrocarbon mAb

Cross-reactivity and multispecific functionality of antibodies play a central role in the immune system. The Ab's promiscuity is attributed to structural flexibility and conformational multiplicity of its binding sites governed by the rearrangement of hydrogen bonding centers. However, antibodi...

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Bibliographic Details
Main Authors: Grubor, Nenad M., Hayes, John, Small, Gerald J., Jankowiak, Ryszard
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140447/
https://ncbi.nlm.nih.gov/pubmed/15888556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502540102
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