Improved Elicitation of Neutralizing Antibodies against Primary Human Immunodeficiency Viruses by Soluble Stabilized Envelope Glycoprotein Trimers

Human immunodeficiency virus (HIV-1) envelope glycoprotein subunits, such as the gp120 exterior glycoprotein, typically elicit antibodies that neutralize T-cell-line-adapted (TCLA), but not primary, clinical isolates of HIV-1. Here we compare the immunogenicity of gp120 and soluble stabilized trimer...

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Bibliografske podrobnosti

izdano v:	J Virol
Principais autores:	Yang, Xinzhen, Wyatt, Richard, Sodroski, Joseph
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2001
Teme:	Vaccines and Antiviral Agents
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114022/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11152489/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.3.1165-1171.2001
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