Caspase Activation by Adenovirus E4orf4 Protein Is Cell Line Specific and Is Mediated by the Death Receptor Pathway

Adenovirus E4orf4 protein has been shown to induce transformed cell-specific, protein phosphatase 2A-dependent, and p53-independent apoptosis. It has been further reported that the E4orf4 apoptotic pathway is caspase-independent in CHO cells. Here, we show that E4orf4 induces caspase activation in t...

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Bibliographic Details
Main Authors: Livne, Adi, Shtrichman, Ronit, Kleinberger, Tamar
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC113975/
https://ncbi.nlm.nih.gov/pubmed/11134292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.2.789-798.2001
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