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Caspase Activation by Adenovirus E4orf4 Protein Is Cell Line Specific and Is Mediated by the Death Receptor Pathway

Adenovirus E4orf4 protein has been shown to induce transformed cell-specific, protein phosphatase 2A-dependent, and p53-independent apoptosis. It has been further reported that the E4orf4 apoptotic pathway is caspase-independent in CHO cells. Here, we show that E4orf4 induces caspase activation in t...

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Pubblicato in:J Virol
Autori principali: Livne, Adi, Shtrichman, Ronit, Kleinberger, Tamar
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2001
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113975/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11134292/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.2.789-798.2001
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