Donor- and Ligand-Dependent Differences in C-C Chemokine Receptor 5 Reexpression

N-terminal modifications of the chemokine RANTES bind to C-C chemokine receptor 5 (CCR5) and block human immunodeficiency virus type 1 (HIV-1) infection with greater efficacy than native RANTES. Modified RANTES compounds induce rapid CCR5 internalization and much slower receptor reexpression than na...

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Autors principals: Sabbe, Rebecca, Picchio, Gastón R., Pastore, Cristina, Chaloin, Olivier, Hartley, Oliver, Offord, Robin, Mosier, Donald E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC113963/
https://ncbi.nlm.nih.gov/pubmed/11134280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.2.661-671.2001
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