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“Resistance” to PSC-RANTES Revisited: Two Mutations in Human Immunodeficiency Virus Type 1 HIV-1(SF162) or Simian-Human Immunodeficiency Virus SHIV(SF162-p3) Do Not Confer Resistance

Resistance of human immunodeficiency virus type 1 (HIV-1) to small-molecule CCR5 inhibitors is well demonstrated, but resistance to macromolecular CCR5 inhibitors (e.g., PSC-RANTES) that act by both CCR5 internalization and receptor blockade had not been reported until recently (3). The report of a...

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Détails bibliographiques
Auteurs principaux: Nedellec, Rebecca, Coetzer, Mia, Lederman, Michael M., Offord, Robin E., Hartley, Oliver, Mosier, Donald E.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876588/
https://ncbi.nlm.nih.gov/pubmed/20335248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01907-09
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