In Vivo Attenuation of Simian Immunodeficiency Virus by Disruption of a Tyrosine-Dependent Sorting Signal in the Envelope Glycoprotein Cytoplasmic Tail

Attenuated simian immunodeficiency viruses (SIVs) have been described that produce low levels of plasma virion RNA and exhibit a reduced capacity to cause disease. These viruses are particularly useful in identifying viral determinants of pathogenesis. In the present study, we show that mutation of...

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Bibliografische gegevens
Hoofdauteurs: Fultz, Patricia N., Vance, Patricia J., Endres, Michael J., Tao, Binli, Dvorin, Jeffrey D., Davis, Ian C., Lifson, Jeffrey D., Montefiori, David C., Marsh, Mark, Malim, Michael H., Hoxie, James A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2001
Onderwerpen:
Pathogenesis and Immunity
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC113922/
https://ncbi.nlm.nih.gov/pubmed/11119598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.1.278-291.2001
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