Overexpression of liver-type phosphofructokinase (PFKL) in transgenic-PFKL mice: implication for gene dosage in trisomy 21.

The human liver-type subunit of the key glycolytic enzyme, phosphofructokinase (PFKL), is encoded by a gene residing on chromosome 21. This chromosome, when triplicated, causes the phenotypic expression of Down's syndrome (trisomy 21). Increased phosphofructokinase activity, a result of gene do...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Elson, A, Levanon, D, Weiss, Y, Groner, Y
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1994
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1138287/
https://ncbi.nlm.nih.gov/pubmed/8172601
Etiketak: Etiketa erantsi
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