Triplex-DNA stabilization by hydralazine and the presence of anti-(triplex DNA) antibodies in patients treated with hydralazine.

Hydralazine is an antihypertensive drug that elicits andti-nuclear antibodies in patients as an adverse effect. We investigated the ability of hydralazine to promote/stabilize the triplex DNA form of poly(dA).2poly(dT). Under conditions of low ionic strength, the polynucleotide melted as a double he...

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Библиографические подробности
Главные авторы: Thomas, T J, Seibold, J R, Adams, L E, Hess, E V
Формат: Artigo
Язык:Inglês
Опубликовано: 1995
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1136136/
https://ncbi.nlm.nih.gov/pubmed/7575452
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