Induction of antibodies to nuclear antigens in rabbits by immunization with hydralazine-human serum albumin conjugates.

The antihypertensive drug hydralazine can induce in man a syndrome similar to spontaneous systemic lupus erythematosus (SLE). The pathogenesis of this drug-induced syndrome is not understood. In this investigation, five groups of rabbits were studied: group I, 10 rabbits hyperimmunized with hydralaz...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Yamauchi, Y, Litwin, A, Adams, L, Zimmer, H, Hess, E V
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1975
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301952/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/808562/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108176
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