DNA-triplex stabilizing properties of 8-aminoguanine

A DNA-triplex stabilizing purine (8-aminoguanine) is designed based on molecular modeling and synthesized. The substitution of guanine by 8-aminoguanine largely stabilizes the triplex both at neutral and acidic pH, as suggested by molecular dynamics and thermodynamic integration calculations, and de...

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Detaylı Bibliyografya
Asıl Yazarlar: Soliva, Robert, Güimil García, Ramón, Blas, J. Ramón, Eritja, Ramon, Asensio, Juan Luis, González, Carlos, Luque, F. Javier, Orozco, Modesto
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2000
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC113881/
https://ncbi.nlm.nih.gov/pubmed/11071942
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