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Semenogelins I and II bind zinc and regulate the activity of prostate-specific antigen
In semen, the gel proteins SgI and SgII (semenogelins I and II) are digested by PSA (prostate-specific antigen), resulting in liquefaction and release of motile spermatozoa. Semen contains a high concentration of Zn(2+), which is known to inhibit the protease activity of PSA. We characterized the bi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1134973/ https://ncbi.nlm.nih.gov/pubmed/15563730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041424 |
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