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Zn(2+) binding to human calbindin D(28k) and the role of histidine residues
We have studied the binding of Zn(2+) to the hexa EF-hand protein, calbindin D(28k)—a strong Ca(2+)-binder involved in apoptosis regulation—which is highly expressed in brain tissue. By use of radioblots, isothermal titration calorimetry, and competition with a fluorescent Zn(2+) chelator, we find t...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2271158/ https://ncbi.nlm.nih.gov/pubmed/18359862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073381108 |
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