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Arginine-482 is not essential for transport of antibiotics, primary bile acids and unconjugated sterols by the human breast cancer resistance protein (ABCG2)

The human BCRP (breast cancer resistance protein, also known as ABCG2) is an ABC (ATP-binding cassette) transporter that extrudes various anticancer drugs from cells, causing multidrug resistance. To study the molecular determinants of drug specificity of BCRP in more detail, we have expressed wild-...

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Bibliografski detalji
Glavni autori: Janvilisri, Tavan, Shahi, Sanjay, Venter, Henrietta, Balakrishnan, Lekshmy, van Veen, Hendrik W.
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd. 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134712/
https://ncbi.nlm.nih.gov/pubmed/15362954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040791
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