Hepatitis C virus non-structural protein NS3 interacts with LMP7, a component of the immunoproteasome, and affects its proteasome activity

NS3, a non-structural protein of the HCV (hepatitis C virus), contains a protease and a helicase domain and plays essential roles in the processing of the viral polyprotein, viral RNA replication and translation. LMP7 (low-molecular-mass protein 7), a component of the immunoproteasome, was identifie...

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Bibliographic Details
Main Authors: Khu, Yee-Ling, Tan, Yee-Joo, Lim, Seng Gee, Hong, Wanjin, Goh, Phuay-Yee
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2004
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134124/
https://ncbi.nlm.nih.gov/pubmed/15303969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040858
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