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C-terminus of mitotic centromere-associated kinesin (MCAK) inhibits its lattice-stimulated ATPase activity

Mitotic centromere-associated kinesin (MCAK) is a microtubule (MT)-destabilizing molecular motor. In the present study we show that the final 8 amino acids of the C-terminus of MCAK inhibit lattice-stimulated ATPase activity of the motor. Surprisingly, loss of this C-terminal ‘tail’ (MCAK-Q710) lead...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Moore, Ayana, Wordeman, Linda
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Portland Press Ltd. 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134063/
https://ncbi.nlm.nih.gov/pubmed/15250824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040736
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