The G115S mutation associated with maturity-onset diabetes of the young impairs hepatocyte nuclear factor 4α activities and introduces a PKA phosphorylation site in its DNA-binding domain

Míreanna Comhchosúla

• Critical role of charged residues in helix 7 of the ligand binding domain in Hepatocyte Nuclear Factor 4α dimerisation and transcriptional activity
  le: Eeckhoute, Jérôme, et al.
  Foilsithe: (2003)
• Hepatocyte Nuclear Factor 4α enhances the Hepatocyte Nuclear Factor 1α-mediated activation of transcription
  le: Eeckhoute, J., et al.
  Foilsithe: (2004)
• The activity of the activation function 2 of the human hepatocyte nuclear factor 4 (HNF-4alpha) is differently modulated by F domains from various origins.
  le: Suaud, L, et al.
  Foilsithe: (1999)
• Mutations in the coding regions of the hepatocyte nuclear factor 4 alpha in Iranian families with maturity onset diabetes of the young
  le: Tavakolafshari Jalil, et al.
  Foilsithe: (2009-12-01)
• Mutations in the coding regions of the hepatocyte nuclear factor 4 alpha in Iranian families with maturity onset diabetes of the young
  le: Taghavi, Seyed Morteza, et al.
  Foilsithe: (2009)