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Brassica juncea 3-hydroxy-3-methylglutaryl (HMG)-CoA synthase 1: expression and characterization of recombinant wild-type and mutant enzymes

3-Hydroxy-3-methylglutaryl (HMG)-CoA synthase (HMGS; EC 2.3.3.10) is the second enzyme in the cytoplasmic mevalonate pathway of isoprenoid biosynthesis, and catalyses the condensation of acetyl-CoA with acetoacetyl-CoA (AcAc-CoA) to yield S-HMG-CoA. In this study, we have first characterized in deta...

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Detalhes bibliográficos
Main Authors: Nagegowda, Dinesh A., Bach, Thomas J., Chye, Mee-Len
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133745/
https://ncbi.nlm.nih.gov/pubmed/15233626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040721
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