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Alternative translation initiation generates a novel isoform of insulin-degrading enzyme targeted to mitochondria
IDE (insulin-degrading enzyme) is a widely expressed zinc-metallopeptidase that has been shown to regulate both cerebral amyloid β-peptide and plasma insulin levels in vivo. Genetic linkage and allelic association have been reported between the IDE gene locus and both late-onset Alzheimer's dis...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Portland Press Ltd.
2004
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1133736/ https://ncbi.nlm.nih.gov/pubmed/15285718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041081 |
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