Alternative translation initiation generates a novel isoform of insulin-degrading enzyme targeted to mitochondria

IDE (insulin-degrading enzyme) is a widely expressed zinc-metallopeptidase that has been shown to regulate both cerebral amyloid β-peptide and plasma insulin levels in vivo. Genetic linkage and allelic association have been reported between the IDE gene locus and both late-onset Alzheimer's dis...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Leissring, Malcolm A., Farris, Wesley, Wu, Xining, Christodoulou, Danos C., Haigis, Marcia C., Guarente, Leonard, Selkoe, Dennis J.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133736/
https://ncbi.nlm.nih.gov/pubmed/15285718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041081
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados