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Inhibition of human coagulation factor VIII by monoclonal antibodies. Mapping of functional epitopes with the use of recombinant factor VIII fragments.

The epitopes of four monoclonal antibodies against coagulation Factor VIII were mapped with the use of recombinant DNA techniques. Full-length Factor VIII cDNA and parts thereof were inserted into the vector pSP64, permitting transcription in vitro with the use of a promoter specific for SP6 RNA pol...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Leyte, A, Mertens, K, Distel, B, Evers, R F, De Keyzer-Nellen, M J, Groenen-Van Dooren, M M, De Bruin, J, Pannekoek, H, Van Mourik, J A, Verbeet, M P
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1989
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133407/
https://ncbi.nlm.nih.gov/pubmed/2481438
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