Differences in 2-oxoglutarate dehydrogenase regulation in liver and kidney.

In response to acidosis, renal ammoniagenesis is stimulated, enhancing urinary buffering power, while hepatic ammoniagenesis and ureagenesis decrease, so as to spare bicarbonate consumed in the urea cycle. 2-Oxoglutarate (2-OG) levels can regulate ammoniagenesis in kidney and gluconeogenesis in live...

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Bibliografiske detaljer
Main Authors: Smith, B C, Clotfelter, L A, Cheung, J Y, LaNoue, K F
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1132613/
https://ncbi.nlm.nih.gov/pubmed/1352447
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