The mechanism of action of DD-peptidases: the role of tyrosine-159 in the Streptomyces R61 DD-peptidase.

Tyrosine-159 of the Streptomyces R61 penicillin-sensitive DD-peptidase was replaced by serine or phenylalanine. The second mutation yielded a very poorly active protein whose rate of penicillin binding was also drastically decreased, except for the reactions with nitrocefin and methicillin. The cons...

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Bibliographische Detailangaben
Hauptverfasser: Wilkin, J M, Jamin, M, Damblon, C, Zhao, G H, Joris, B, Duez, C, Frère, J M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1993
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1132558/
https://ncbi.nlm.nih.gov/pubmed/8484734
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