Studies on the inhibitory mechanism of iodonium compounds with special reference to neutrophil NADPH oxidase.

Diphenyleneiodonium (DPI) and its analogues have been previously shown to react via a radical mechanism whereby an electron is abstracted from a nucleophile to form a radical, which then adds back to the nucleophile to form covalent adducts [Banks (1966) Chem. Rev. 66, 243-266]. We propose that the...

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Библиографические подробности
Главные авторы: O'Donnell, B V, Tew, D G, Jones, O T, England, P J
Формат: Artigo
Язык:Inglês
Опубликовано: 1993
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1132380/
https://ncbi.nlm.nih.gov/pubmed/8439298
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