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Neutrophils to the ROScue: Mechanisms of NADPH Oxidase Activation and Bacterial Resistance

Reactive oxygen species (ROS) generated by NADPH oxidase play an important role in antimicrobial host defense and inflammation. Their deficiency in humans results in recurrent and severe bacterial infections, while their unregulated release leads to pathology from excessive inflammation. The release...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Nguyen, Giang T., Green, Erin R., Mecsas, Joan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574878/
https://ncbi.nlm.nih.gov/pubmed/28890882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00373
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