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Neutrophils to the ROScue: Mechanisms of NADPH Oxidase Activation and Bacterial Resistance

Reactive oxygen species (ROS) generated by NADPH oxidase play an important role in antimicrobial host defense and inflammation. Their deficiency in humans results in recurrent and severe bacterial infections, while their unregulated release leads to pathology from excessive inflammation. The release...

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Veröffentlicht in:Front Cell Infect Microbiol
Hauptverfasser: Nguyen, Giang T., Green, Erin R., Mecsas, Joan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574878/
https://ncbi.nlm.nih.gov/pubmed/28890882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00373
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