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Characterization of the bacterial metalloendopeptidase pitrilysin by use of a continuous fluorescence assay.

Pitrilysin (EC 3.4.99.44) has been purified from an over-expressing strain of Escherichia coli. A 13-residue quenched-fluorescent-peptide substrate for the enzyme has been synthesized, and found also to be cleaved by the homologous enzyme, insulinase (EC 3.4.99.45). The action of pitrilysin on pepti...

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Autors principals: Anastasi, A, Knight, C G, Barrett, A J
Format: Artigo
Idioma:Inglês
Publicat: 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1132317/
https://ncbi.nlm.nih.gov/pubmed/7680857
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