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Differential activation of p44mapk (ERK1) by alpha-thrombin and thrombin-receptor peptide agonist.

alpha-Thrombin (thrombin), a potent mitogen for CCL39 hamster lung fibroblasts, stimulates phosphoinositide-specific phospholipase C (PI-PLC) and inhibits adenylate cyclase via cleavage of a specific G-protein-coupled receptor (TH-R), recently cloned from human and hamster cells. This action can be...

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Autores principales: Vouret-Craviari, V, Van Obberghen-Schilling, E, Scimeca, J C, Van Obberghen, E, Pouysségur, J
Formato: Artigo
Lenguaje:Inglês
Publicado: 1993
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1132151/
https://ncbi.nlm.nih.gov/pubmed/8380983
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