p38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes

Adult mammalian cardiomyocytes are considered terminally differentiated and incapable of proliferation. Consequently, acutely injured mammalian hearts do not regenerate, they scar. Here, we show that adult mammalian cardiomyocytes can divide. One important mechanism used by mammalian cardiomyocytes...

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Autors principals: Engel, Felix B., Schebesta, Michael, Duong, Mychelle T., Lu, Gang, Ren, Shuxun, Madwed, Jeffery B., Jiang, Huiping, Wang, Yibin, Keating, Mark T.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2005
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1132004/
https://ncbi.nlm.nih.gov/pubmed/15870258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1306705
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