טוען...

Disruption of Virion Host Shutoff Activity Improves the Immunogenicity and Protective Capacity of a Replication-Incompetent Herpes Simplex Virus Type 1 Vaccine Strain

The virion host shutoff (vhs) protein encoded by herpes simplex virus type 1 (HSV-1) destabilizes both viral and host mRNAs. An HSV-1 strain with a mutation in vhs is attenuated in virulence and induces immune responses in mice that are protective against corneal infection with virulent HSV-1, but i...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Geiss, Brian J., Smith, Tracy J., Leib, David A., Morrison, Lynda A.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2000
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC113198/
https://ncbi.nlm.nih.gov/pubmed/11070010
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!