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Somatostatin inhibition of Ca2(+)-induced insulin secretion in permeabilized HIT-T15 cells.

Somatostatin inhibited Ca2(+)-induced insulin secretion in permeabilized HIT-T15 cells, albeit with decreased sensitivity relative to intact cells. The inhibitory action required the presence of GTP, whereas GDP could not substitute for GTP. Pertussis-toxin treatment before cell permeabilization abo...

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Bibliografische gegevens
Hoofdauteurs: Ullrich, S, Prentki, M, Wollheim, C B
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1990
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1131711/
https://ncbi.nlm.nih.gov/pubmed/1975739
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