Somatostatin-induced paradoxical increase in intracellular Ca2+ concentration and insulin release in the presence of arginine vasopressin in clonal HIT-T15 beta-cells.

Somatostatin, a hormone that signals via G(i)/G(o), usually inhibits increases in intracellular calcium concentration ([Ca(2+)](i)) and insulin release from beta-cells. We have found that in the presence of arginine vasopressin (AVP), which signals via G(q), somatostatin increased [Ca(2+)](i), leadi...

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Hauptverfasser: Cheng, Henrique, Yibchok-Anun, Sirintorn, Park, Seung-Chun, Hsu, Walter H
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2002
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222542/
https://ncbi.nlm.nih.gov/pubmed/11988073
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