Pre-steady state kinetics of bacteriophage T4 Dam DNA-[N(6)-adenine] methyltransferase: interaction with native (GATC) or modified sites

The DNA methyltransferase of bacteriophage T4 (T4 Dam MTase) recognizes the palindromic sequence GATC, and catalyzes transfer of the methyl group from S-adenosyl-l-methionine (AdoMet) to the N(6)-position of adenine [generating N(6)-methyladenine and S-adenosyl-l-homocysteine (AdoHcy)]. Pre-steady s...

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Hauptverfasser: Malygin, Ernst G., Lindstrom, William M., Schlagman, Samuel L., Hattman, Stanley, Reich, Norbert O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2000
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC113137/
https://ncbi.nlm.nih.gov/pubmed/11058118
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