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Regulation of cardiac adenylate cyclase activity in rodent models of obesity.

We have investigated beta-adrenergic regulation of adenylate cyclase activity in heart tissue membranes from the genetically obese Zucker rat, the genetically obese CBA mouse and the genetically obese diabetic (db/db) mouse. Responsiveness to beta-adrenergic stimulation was impaired in membranes fro...

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Bibliographic Details
Main Authors: Strassheim, D, Houslay, M D, Milligan, G
Format: Artigo
Language:Inglês
Published: 1992
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1131015/
https://ncbi.nlm.nih.gov/pubmed/1348926
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