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Simple model for hormone-activated adenylate cyclase systems.

A simple model is developed to explain the activation of rat liver plasma membrane adenylate cyclase [ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1] by guanosine nucleotides and glucagon and the dependence of the cATALYTIC RATE ON Mg2+, H+, and substrate concentrations. The basic model proposes th...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Hammes, G G, Rodbell, M
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1976
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC430226/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4796/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.4.1189
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