Infection of Neonatal Mice with Sindbis Virus Results in a Systemic Inflammatory Response Syndrome

Laboratory strains of viruses may contain cell culture-adaptive mutations which result in significant quantitative and qualitative alterations in pathogenesis compared to natural virus isolates. This report suggests that this is the case with Sindbis virus strain AR339. A cDNA clone comprising a con...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Klimstra, W. B., Ryman, K. D., Bernard, K. A., Nguyen, K. B., Biron, C. A., Johnston, R. E.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1999
Schlagworte:	Pathogenesis and Immunity
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113094/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10559357/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.12.10387-10398.1999
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