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Infection of Neonatal Mice with Sindbis Virus Results in a Systemic Inflammatory Response Syndrome

Laboratory strains of viruses may contain cell culture-adaptive mutations which result in significant quantitative and qualitative alterations in pathogenesis compared to natural virus isolates. This report suggests that this is the case with Sindbis virus strain AR339. A cDNA clone comprising a con...

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Detalhes bibliográficos
Main Authors: Klimstra, W. B., Ryman, K. D., Bernard, K. A., Nguyen, K. B., Biron, C. A., Johnston, R. E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC113094/
https://ncbi.nlm.nih.gov/pubmed/10559357
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