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The Role of Interferon in Influenza Virus Tissue Tropism

We have studied the pathogenesis of influenza virus infection in mice that are unable to respond to type I or II interferons due to a targeted disruption of the STAT1 gene. STAT1−/− animals are 100-fold more sensitive to lethal infection with influenza A/WSN/33 virus than are their wild-type (WT) co...

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Publicado no:J Virol
Principais autores: García-Sastre, Adolfo, Durbin, Russell K., Zheng, Hongyong, Palese, Peter, Gertner, Rachel, Levy, David E., Durbin, Joan E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1998
Assuntos:
Viral Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110265/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9765393/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.11.8550-8558.1998
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