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Use of a gp120 Binding Assay To Dissect the Requirements and Kinetics of Human Immunodeficiency Virus Fusion Events

Binding of the extracellular subunit of human immunodeficiency type 1 (HIV-1) envelope (Env) glycoprotein (gp120) to CD4 triggers the induction or exposure of a highly conserved coreceptor binding site in gp120 that helps mediate membrane fusion. Characterizing the structural features involved in gp...

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Détails bibliographiques
Auteurs principaux: Doranz, Benjamin J., Baik, Sarah S. W., Doms, Robert W.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC113090/
https://ncbi.nlm.nih.gov/pubmed/10559353
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