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Human Immunodeficiency Virus Type 1 Attachment to HeLa CD4 Cells Is CD4 Independent and gp120 Dependent and Requires Cell Surface Heparans

The binding of human immunodeficiency virus type 1 (HIV-1) (Hx10) virions to two different cell lines was analyzed by using a novel assay based on the detection, by anti-HLA-DR-specific antibodies, of HLA-DR(+) virus binding to HLA-DR(−) cells. Virion attachment to the CD4(+)-T-cell line A3.01 was h...

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Detalhes bibliográficos
Main Authors: Mondor, Isabelle, Ugolini, Sophie, Sattentau, Quentin J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC109583/
https://ncbi.nlm.nih.gov/pubmed/9557643
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