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Human Immunodeficiency Virus Type 1 Attachment to HeLa CD4 Cells Is CD4 Independent and gp120 Dependent and Requires Cell Surface Heparans

The binding of human immunodeficiency virus type 1 (HIV-1) (Hx10) virions to two different cell lines was analyzed by using a novel assay based on the detection, by anti-HLA-DR-specific antibodies, of HLA-DR(+) virus binding to HLA-DR(−) cells. Virion attachment to the CD4(+)-T-cell line A3.01 was h...

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Pubblicato in:J Virol
Autori principali: Mondor, Isabelle, Ugolini, Sophie, Sattentau, Quentin J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1998
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109583/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9557643/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.5.3623-3634.1998
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