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Multiphasic generation of diacylglycerol in thrombin-activated human platelets.

The diacylglycerol (DAG)/protein kinase C pathway plays an important role in platelet aggregation and granule secretion. In this study, we examined the detailed kinetics of DAG formation in response to platelet stimulation. Both alpha- and gamma-thrombin caused multiphasic generation of DAG mass, wi...

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Detalhes bibliográficos
Main Authors: Werner, M H, Bielawska, A E, Hannun, Y A
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1130860/
https://ncbi.nlm.nih.gov/pubmed/1554365
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