Efficient trans-Complementation of the Flavivirus Kunjin NS5 Protein but Not of the NS1 Protein Requires Its Coexpression with Other Components of the Viral Replicase

Successful trans-complementation of the defective Kunjin virus (KUN) RNA FLdGDD with a deletion of the RNA polymerase motif GDD in the NS5 gene by using a BHK cell line, repBHK, that continuously produced a functionally active KUN replication complex (RC) from replicon RNA was recently reported (A....

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Khromykh, Alexander A., Sedlak, Petra L., Guyatt, Kimberley J., Hall, Roy A., Westaway, Edwin G.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Replication
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113081/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10559344/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.12.10272-10280.1999
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